Hi, my name is Florian and I am currently working as a Postdoc at the institute for computational biomedicine in the group of Dr. Denis Schapiro. My current projects are focused on utilizing spatial OMICS to better understand cell-cell interactions in human diseases and how to utilize this exciting technology to better understand disease pathology. One of my key interests is the genetic basis of cardiovascular disease, particularly congenital heart disease, coronary artery disease and heart valve disease. I have utilized multi-OMICS, including highly-multiplexed imaging, single-cell technologies and CRISPR gene editing to better understand the molecular basis of these conditions and to identify potential treatment targets. During my PhD I have utilized whole-exome sequencing to identify candidate genes for congenital heart disease, helped in setting-up a single-cell platform (Drop-seq) and investigating a novel candidate gene for heart valve disease in the lab of Prof. Gregor Andelfinger at the CHU Ste Justine research center.
Beside my work, I am also extremely interested in using data science to analyze sports data, particularly football (soccer). I am a passionate supporter of Borussia Dortmund ever since I was young and love watching and playing soccer myself.
🧬 💻 👨🔬 🧪 🔬 ⚽ 🎮 🇩🇪
PhD in Life Sciences, 2018
University of Muenster / CHU Ste Justine Research Center
MSc in Life Sciences, 2014
University of Muenster
tidyverse, single-cell OMICS, genomics, building Rshiny apps, package building
basic computer vision, single-cell analysis
My favourite OS
Molecular cloning, CRISPR, Rare & common diseases
Valve diseases, Coronary artery disease, Congenital heart diseases
Docker, Singularity, Nextflow
Projects:
Projects:
Title: The role of genetic factors in pathogenesis and progression of cardiac malformations
Projects:
Passion project on building soccer computer vision and data analysis tools for my local Montreal group
The Canadian Portal for Life Sciences Computing
Rshiny app for single-cell analysis and visualization